Intergenerational effects of hyperglycaemia in pregnancy: the PANDORA Wave 1 study

Aims:

To compare growth, cardiometabolic risk factors and developmental risk of children born to mothers with hyperglycaemia in pregnancy (HIP) to those born to mothers without HIP.

Objectives:

The project has 4 objectives, to:

1. Describe growth (height, weight, BMI) in 18-60 month old children born to mothers with and without HIP, involving the whole PANDORA cohort.
2. Examine anthropometry and nutritional indicators in a subgroup of 18-60 month old children born to mothers with HIP and compare to a subgroup of children of mothers without HIP (Pandora Wave 1). Anthropometric data includes height, weight, BMI, skinfold thicknesses, body part circumferences and bio-impedance.
3. Examine cardio-metabolic risk factors in a subgroup of 18-60 month old children born to mothers with HIP and compare to a subgroup of children of mothers without HIP (Pandora Wave 1), exploring early childhood predictors of later cardio-metabolic disease.
4. Describe developmental risk in a sub-group of 18-60 month old children born to mothers with HIP and compare to a subgroup of children of mothers without HIP (Pandora Wave 1).